Post #5224

Bacterial strain from 5,000-year-old cave ice shows resistance against 10 modern antibiotics Bacteria have evolved to adapt to all of Earth's most extreme conditions, from scorching heat to temperatures well below zero. Ice caves are just one of the environments hosting a variety of microorganisms that represent a source of genetic diversity that has not yet been studied extensively. Now, researchers in Romania tested antibiotic resistance profiles of a bacterial strain that until recently was hidden in a 5,000-year-old layer of ice of an underground ice cave—and found it could be an opportunity for developing new strategies to prevent the rise of antibiotic resistance and study how resistance naturally evolves and spreads. They reported their discovery in Frontiers in Microbiology. "The Psychrobacter SC65A.3 bacterial strain isolated from Scarisoara Ice Cave, despite its ancient origin, shows resistance to multiple modern antibiotics and carries over 100 resistance-related genes," said author Dr. Cristina Purcarea, a senior scientist at the Institute of Biology Bucharest of the Romanian Academy. "But it can also inhibit the growth of several major antibiotic-resistant 'superbugs' and showed important enzymatic activities with important biotechnological potential." Ancient resistance to modern medication Psychrobacter SC65A.3 is a strain of the genus Psychrobacter, which are bacteria adapted to cold environments. Some species can cause infections in humans or animals. Psychrobacter bacteria have biotechnological potential, but the antibiotic resistance profiles of these bacteria are largely unknown. "Studying microbes such as Psychrobacter SC65A.3 retrieved from millennia-old cave ice deposits reveals how antibiotic resistance evolved naturally in the environment, long before modern antibiotics were ever used," said Purcarea. Source:Phys.org @EverythingScience