Попробовали настольный Slay the Spire, и мне очень понравилось.
Кто не знает, Slay the Spire это изначально инди-видеоигра в жанре «роглайк на построение колоды». Нарисована она совсем простовато (не пиксель арт, и то хорошо), зато обладает своего рода эталонным геймдизайном. Там нет ничего лишнего, но есть всё нужное. Причём, большинство эффектов считается в уме, а пространство решений для игрока всё равно очень большое. Попытки других разработчиков скопировать эту игру и добавить в неё что-то дополнительное («Чёрная Книга», «Knock on the Coffin Lid») сразу показали, что результат становится сильно хуже.
Короче, если вам нужна игра не про «спинномозговой» геймплей, а про шевеление головой, при этом позволяющая зайти на 15 минуток в день сыграть пару боёв, реиграбельная и не зависящая от присутствия задротов (в отличие от онлайн игр), то это очень хороший вариант.
Поэтому, когда вышла настолка, вопрос о покупке не стоял. Да, настолки по видеоиграм нередко оказываются довольно вторичными и либо не предлагают ничего принципиально нового, либо, наоборот, переиначивают первоисточник сверх меры. Здесь у меня тоже были определённые опасения, например, о том, что потребуется перекладывать слишком много компонентов там, где в видеоигре действия выполнял компьютер.
К счастью, опасения не подтвердились, и авторы очень хорошо поработали над адаптацией: все числа уменьшили, сократили математику, упростили эффекты, не сломав их качественную суть, и добавили кооператив, который действительно играет роль. Прибавьте к этому приятные ощущения от того, что ты не на экране на карточки смотришь, а листаешь их в руках, плюс возможность разделить эмоции и тяготы прохождения с друзьями.
В общем, прямо очень порадовало. #games@clockstackwheels
#intermediate
📌 made my day
Meaning 👉 To cause one to feel very happy; to be a very positive highlight of one's day.
Example
When my neighbors surprised me with homemade chocolate chip cookies, it is really made my day.
@English_Speakers
#Intermediate
@English_Speakers
📌 When the cat a way the mice will play
غاب القط فالعب يا فار
people being supervised often do things they are not supposed to do when the supervising person is not around (expression often used in a humorous way about employer and employees, parents and children, etc.)
👉Example:
"“His parents are away for the weekend.” “I see—while the cat's away.”
@English_Speakers
New Psychedelics compounds search.
Why?
Deal with First gen psychedelic issues:
- they were not created specifically to threat a particular disorder even if can do it with a certain efficacy
- they have cardiotoxicity related to 5ht2b mechanism
- long action duration length for therapy
New hopes and ideas:
- decouple halucenogetic from therapeutic effect
- potentially reaching even newer states of mind
- targetly engineered experience without so complex set and setting
What?
- Kanna alcaloids for premature ejaculation 😅
- BPL-003 for Treatment Resistant Depression (TRD).
- IHCH-7113 Non halucenogetic psychedelic for depression
- Ele-101 for depression and Alcohol Use Disorder (AUD).
How?
1. AI assisted search
- Predictive AI. Train on structure to properties (need big dataset of both)
- Generative AI. Evolutionary machines
2. Natural compounds search and enchantment
- Research existing less popular natural compounds rom indigenous communities
- Enchance properties (Increase a half life, change blood barrier penetration, etc..
3. Future approaches
- computational chemistry (compounds VS receptors )
- test on brain organoids
Skill level: #intermediate
https://youtu.be/BQoIozpBU5Y
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/NjgxMmNkZTUtYThmZi00OWIxLThkMmMtZGU5NGM4MDQ2YjRl?ep=14
Why MDMA analogs?
1. Safer options for mory risky categories of people:
People with Cardiac deseas history
People over the age of 65
2. Other medical application apart form PTD
Social anxiety for Autism
Parkinson's desease
3. Other impoovements
Shorter therapy duration
More cheaper production
Skill level: #intermediate
Researchers Are Mapping DMT Dimensions Through DMTx Tech
Seems like DMTX is finally started and we will see more exciting news from various labs all over the world.
Any friends anesthesiologists?😁
"But that doesn’t mean we can’t have some kind of mapping. One can think about Level mapping for example, so do different levels of intensity experience reliably take you to different types of spaces? Is there a progression? I mean people talk already, about you know, moving to the waiting room and then the dome. There has already been developed in a very informal sense, a certain kind of mapping of the space.”
Skill level #intermediate
https://psychedelicspotlight.com/researchers-are-mapping-out-new-dimensions-through-dmtx-technology/
1️⃣How often does he work?
Everyday
All day
Rarely
2️⃣What is he starting to think about?
Playing basketball
Watching TV
His health
Work
3️⃣What decision is made to get more exercise?
Running or Jogging
Doing more outdoor activities
Going to the local gym
4️⃣What type of lessons are they considering?
Dance
Tennis
Basketball
5️⃣For $120, How often will they meet?
Everyday for a month
Once a week for two months
Every afternoon
Twice a week for one month
6️⃣Please fill the blank and tell me what does whole sentence mean?
Playing tennis twice a week will be a good start. ..... me .... .
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy
🟧🔷 Listening Activity🔷🟧
Please listen to the audio twice and then answer the following questions.
✍️You can find the transcript below later.
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy
1️⃣How often does he work?
Everyday
All day
Rarely
2️⃣What is he starting to think about?
Playing basketball
Watching TV
His health
Work
3️⃣What decision is made to get more exercise?
Running or Jogging
Doing more outdoor activities
Going to the local gym
4️⃣What type of lessons are they considering?
Dance
Tennis
Basketball
5️⃣For $120, How often will they meet?
Everyday for a month
Once a week for two months
Every afternoon
Twice a week for one month
6️⃣Please fill the blank and tell me what does whole sentence mean?
Playing tennis twice a week will be a good start. ..... me .... .
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy
🟧🔷 Listening Activity🔷🟧
Please listen to the audio twice and then answer the following questions.
✍️You can find the transcript below later.
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy
1️⃣How often does he work?
Everyday
All day
Rarely
2️⃣What is he starting to think about?
Playing basketball
Watching TV
His health
Work
3️⃣What decision is made to get more exercise?
Running or Jogging
Doing more outdoor activities
Going to the local gym
4️⃣What type of lessons are they considering?
Dance
Tennis
Basketball
5️⃣For $120, How often will they meet?
Everyday for a month
Once a week for two months
Every afternoon
Twice a week for one month
6️⃣Please fill the blank and tell me what does whole sentence mean?
Playing tennis twice a week will be a good start. ..... me .... .
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy
🟧🔷 Listening Activity🔷🟧
Please listen to the audio twice and then answer the following questions.
✍️You can find the transcript below later.
#Listening
#Intermediate
#Teamjimmy
@Sirjimmy