Psychedelic Consciousness ( ex Unstoppable Technologies)

New Psychedelics compounds search. Why? Deal with First gen psychedelic issues: - they were not created specifically to threat a particular disorder even if can do it with a certain efficacy - they have cardiotoxicity related to 5ht2b mechanism - long action duration length for therapy New hopes and ideas: - decouple halucenogetic from therapeutic effect - potentially reaching even newer states of mind - targetly engineered experience without so complex set and setting What? - Kanna alcaloids for premature ejaculation 😅 - BPL-003 for Treatment Resistant Depression (TRD). - IHCH-7113 Non halucenogetic psychedelic for depression - Ele-101 for depression and Alcohol Use Disorder (AUD). How? 1. AI assisted search - Predictive AI. Train on structure to properties (need big dataset of both) - Generative AI. Evolutionary machines 2. Natural compounds search and enchantment - Research existing less popular natural compounds rom indigenous communities - Enchance properties (Increase a half life, change blood barrier penetration, etc.. 3. Future approaches - computational chemistry (compounds VS receptors ) - test on brain organoids Skill level: #intermediate https://youtu.be/BQoIozpBU5Y

https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5saWJzeW4uY29tLzgxODk1L3Jzcw/episode/NjgxMmNkZTUtYThmZi00OWIxLThkMmMtZGU5NGM4MDQ2YjRl?ep=14 Why MDMA analogs? 1. Safer options for mory risky categories of people: People with Cardiac deseas history People over the age of 65 2. Other medical application apart form PTD Social anxiety for Autism Parkinson's desease 3. Other impoovements Shorter therapy duration More cheaper production Skill level: #intermediate

Researchers Are Mapping DMT Dimensions Through DMTx Tech Seems like DMTX is finally started and we will see more exciting news from various labs all over the world. Any friends anesthesiologists?😁 "But that doesn’t mean we can’t have some kind of mapping. One can think about Level mapping for example, so do different levels of intensity experience reliably take you to different types of spaces? Is there a progression? I mean people talk already, about you know, moving to the waiting room and then the dome. There has already been developed in a very informal sense, a certain kind of mapping of the space.” Skill level #intermediate https://psychedelicspotlight.com/researchers-are-mapping-out-new-dimensions-through-dmtx-technology/

https://youtu.be/ba5pAjM8HZM Skill level #intermediate